Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[A young patient with multiple arterial occlusions]

C Panzere1, A Brieke, B Bräuer

  • 1Medizinische Abteilung für Endokrinologie, Stoffwechsel Und Angiologie, Städtisches Krankenhaus München-neuperlach.

Medizinische Klinik (Munich, Germany : 1983)
|June 19, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Speed limit of the insulator-metal transition in magnetite.

Nature materials·2013
Same author

Images of a spin-torque-driven magnetic nano-oscillator.

Physical review letters·2011
Same author

Reaction chemistry of 1,1'-ferrocene dicarboxylate towards M(ii) salts (M = Co, Ni, Cu): solid-state structure and electrochemical, electronic and magnetic properties of bi- and tetrametallic complexes and coordination polymers.

Dalton transactions (Cambridge, England : 2003)·2009
Same author

Mid-IR spectra of different conformers of phenylalanine in the gas phase.

Physical chemistry chemical physics : PCCP·2008
Same author

Intussusception: still a surgical disease in Africa.

Tropical doctor·2007
Same author

Does contrast medium administration in organ donors affect early kidney graft function?

Transplantation proceedings·2006

Mild hyperhomocysteinemia is a significant risk factor for premature arterial occlusive disease. This case highlights its role in a young female with multiple arterial occlusions, emphasizing the need for considering this condition in diagnosis.

Area of Science:

  • Vascular Medicine
  • Cardiovascular Disease
  • Metabolic Disorders

Background:

  • Mild hyperhomocysteinemia, stemming from genetic or nutritional factors, is a recognized independent risk factor for premature arterial occlusive disease.
  • Arterial occlusive disease can manifest in various vascular beds, impacting organs such as the intestines and extremities.

Observation:

  • A 27-year-old female presented with symptoms of acute limb ischemia and a history of recurrent small bowel ileus.
  • Angiography identified occlusions in the popliteal artery, superior mesenteric artery, and celiac trunk.
  • Patient risk factors included smoking, oral contraceptive use, and elevated homocysteine levels.

Findings:

  • Conservative treatment with prostaglandins and physical therapy was initiated.

Related Experiment Videos

  • Oral supplementation with folate and B vitamins normalized homocysteine levels after 4 weeks.
  • No genetic defect in homocysteine metabolism enzymes was identified.

    • Implications:

    • This case underscores the importance of considering mild hyperhomocysteinemia in the differential diagnosis of premature arterial occlusive disease, even in young patients.
    • Effective management of hyperhomocysteinemia through vitamin supplementation can potentially mitigate vascular risks.
    • Further investigation into non-genetic causes of hyperhomocysteinemia is warranted in such cases.