Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Amineptine and midazolam dependence

I Perera1, L Lim

  • 1Department of Psychological Medicine, National University Hospital, Singapore.

Singapore Medical Journal
|June 20, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Soil health improvements under cover crops are associated with enhanced soil content of cytokinins.

Plant biology (Stuttgart, Germany)·2024
Same author

Early onset metastatic colorectal cancer in Australia.

Cancer treatment and research communications·2024
Same author

Targeting antimicrobial stewardship in hospitalised patients with community-acquired pneumonia within 24 h of admission.

Infection, disease & health·2024
Same author

Aflibercept monotherapy versus aflibercept with targeted retinal laser to peripheral retinal ischemia for diabetic macular oedema (LADAMO).

Eye (London, England)·2023
Same author

Re-evaluation of the low-dose dexamethasone suppression test in dogs.

The Journal of small animal practice·2022
Same author

Safety of the use of gold nanoparticles conjugated with proinsulin peptide and administered by hollow microneedles as an immunotherapy in type 1 diabetes.

Immunotherapy advances·2022

This case report details amineptine and midazolam dependence, highlighting amineptine as a potential drug of abuse. It is the first reported local case, prompting a review of similar substance abuse incidents.

Area of Science:

  • Pharmacology
  • Clinical Toxicology
  • Case Reports

Background:

  • Amineptine, an antidepressant, has been associated with abuse potential.
  • Midazolam is a benzodiazepine with known dependence risks.
  • Understanding combined substance dependence is crucial for clinical management.

Observation:

  • A case of co-dependence on amineptine and midazolam is presented.
  • The patient's clinical presentation and diagnostic investigations were documented.
  • This represents the first reported instance of amineptine abuse in the local region.

Findings:

  • Amineptine abuse can manifest with specific clinical and investigative findings.
  • Comparison with existing literature reveals patterns in amineptine abuse presentations.

Related Experiment Videos

  • The case underscores the potential for amineptine to be misused as a recreational drug.

    • Implications:

    • Clinicians should be vigilant for amineptine abuse, especially in patients with co-occurring substance use.
    • This report emphasizes the need for increased awareness and monitoring of amineptine's abuse potential.
    • Further research into the neurobiological mechanisms of amineptine dependence is warranted.