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Patient-controlled anesthesia for colonoscopy using propofol: results of a pilot study
D R Heiman1, B A Tolliver, F R Weis
1Department of Anesthesia, University of South Alabama College of Medicine, Mobile 36617, USA.
Southern Medical Journal
|June 20, 1998
Summary
Patient-controlled anesthesia (PCA) is feasible for colonoscopy sedation. Combining propofol with alfentanil effectively managed pain, unlike propofol alone, ensuring patient comfort during the procedure.
Area of Science:
- Anesthesiology
- Gastroenterology
- Medical Devices
Background:
- Investigating the use of patient-controlled anesthesia (PCA) for conscious sedation during colonoscopy procedures.
- Assessing the safety and efficacy of PCA in an endoscopic setting.
Purpose of the Study:
- To determine the feasibility of patient-controlled anesthesia for conscious sedation during colonoscopy.
- To evaluate the effectiveness of different propofol and alfentanil dosing regimens via PCA.
Main Methods:
- Elective colonoscopy patients received medications via PCA pump (Abbot Lifecare Provider 5500).
- Three groups received varying doses of propofol alone or in combination with alfentanil.
- Continuous monitoring of vital signs (blood pressure, pulse rate, ECG, respiratory rate) was performed.
Main Results:
- No clinically significant adverse changes in vital signs were observed.
- No sedation-related adverse effects or colonoscopy complications occurred.
- While recovery was rapid, patient recall persisted; propofol alone provided moderate pain relief, whereas the propofol-alfentanil combination offered better pain control.
Conclusions:
- Patient-controlled anesthesia is a viable option for sedation in endoscopic procedures.
- Propofol monotherapy was insufficient for adequate pain relief during colonoscopy.
- The combination of propofol and alfentanil administered via PCA demonstrated effective pain management.