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Nucleocytoplasmic transport: driving and directing transport
1Department of Biochemistry, Dartmouth Medical School, Hanover, New Hampshire 03755, USA. charles.cole@dartmouth.edu
Current Biology : CB
|June 23, 1998
Abstract:
Nucleocytoplasmic transport involves assembly and movement across the nuclear envelope of cargo-receptor complexes that interact with the small GTPase Ran. The asymmetric distribution of Ran regulator proteins, RanGAP1 and RCC1, provides the driving force and directionality for nuclear transport.