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Visual improvement during octreotide therapy in a case of episellar meningioma
M L Jaffrain-Rea1, G Minniti, A Santoro
1Dipartimento di Medicina Sperimentale, Università degli Studi, L'Aquila (AQ), Italy.
Clinical Neurology and Neurosurgery
|June 24, 1998
Abstract:
Meningiomas of the tuberculum sellae can induce compression of the optic tract. We report the case of a 54-year-old female patient affected by a suspected pituitary macroadenoma with severe visual field defects, who experienced a significant clinical and visual improvement during short-term octreotide therapy, contrasting with the lack of neuroradiological evidence for tumor shrinkage. The patient subsequently underwent transcranial surgery with a final diagnosis of meningioma. The putative mechanisms of visual improvement during octreotide therapy are discussed.