Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiple subpial transection in patients with extratemporal epilepsy

M C Smith1

  • 1Department of Neurological Sciences, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612-3824, USA.

Epilepsia
|June 24, 1998
PubMed
Summary

Multiple subpial transection (MST) offers a safe and effective treatment for partial epilepsies near critical brain areas. This surgical technique provides seizure control comparable to resection without impacting daily activities.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Using rotifer population demographic parameters to assess impacts of the degradation products from trinitrotoluene phytoremediation.

Ecotoxicology and environmental safety·2003
Same author

Predictors of 90-day outcome in patients stabilized after acute coronary syndromes.

European heart journal·2003
Same author

Refinement of the nickel site structure in Desulfovibrio gigas hydrogenase using range-extended EXAFS spectroscopy.

Journal of inorganic biochemistry·2003
Same author

'See and treat' at colposcopy--achieving the standard.

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology·2003
Same author

Hypertension in hemodialysis patients.

Current hypertension reports·2001
Same author

Quantification of neurologic function.

Critical care medicine·2001

Area of Science:

  • Neurosurgery
  • Epileptology
  • Neuroscience

Background:

  • Partial epilepsies often involve eloquent cortex (language, sensorimotor areas), posing challenges for surgical treatment.
  • Understanding neocortical columnar organization and seizure spread via transverse fibers informed the development of new surgical approaches.
  • Traditional resective surgery carries risks of neurological deficits when near critical brain regions.

Purpose of the Study:

  • To evaluate the efficacy and safety of Multiple Subpial Transection (MST) for treating partial epilepsies affecting eloquent cortex.
  • To compare the outcomes of MST with those of traditional resective surgery in extratemporal epilepsy.
  • To assess the impact of MST on patients' activities of daily living.

Main Methods:

  • Multiple Subpial Transection (MST) procedure, involving transecting the cortical surface.

Related Experiment Videos

  • Surgical intervention for partial epilepsies located in or encroaching upon eloquent cortex.
  • Comparative analysis of seizure control and functional outcomes between MST and resective surgery.

    • Main Results:

    • MST demonstrates comparable efficacy to resective surgery in controlling seizures in extratemporal epilepsy.
    • The procedure preserves neurological function, with no adverse impact on activities of daily living.
    • Successful application of MST requires technical skill to preserve neocortical columns and vascular supply.

    Conclusions:

    • Multiple Subpial Transection (MST) is a viable and effective surgical alternative to resection for partial epilepsies involving eloquent cortex.
    • MST offers a method to treat epilepsy in critical brain areas while preserving neurological function.
    • The technique's success relies on precise execution by experienced surgeons to minimize collateral damage.