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[Duphalac (lactulose) in the treatment of chronic constipation in children]
1Oddział Dzieciecy Szpitala Wojewódzkiego Nr 2, Rzeszowie.
Insights
Duphalac effectively treats functional chronic constipation in children, improving stool consistency and bowel regularity within weeks. This study found it safe and well-tolerated, with minimal taste issues reported.
Area of Science:
- Pediatrics
- Gastroenterology
- Pharmacology
Background:
- Functional chronic constipation is a common pediatric issue.
- Lactulose-based preparations are frequently used for constipation management.
Purpose of the Study:
- To evaluate the efficacy and safety of Duphalac in treating functional chronic constipation in pediatric patients.
Main Methods:
- A study involving 112 children aged 10 months to 15.5 years.
- Assessment of Duphalac's effectiveness on constipation symptoms and patient tolerance.
Main Results:
- Duphalac demonstrated high effectiveness, rapidly improving peristalsis and defecation rhythm in approximately 2.5 weeks.
- Key improvements included stool softening, pain reduction, resolution of encopresis, and enhanced appetite.
- Only two patients reported taste as an issue; no undesirable side effects were observed.
Conclusions:
- Duphalac is a highly effective and safe treatment option for functional chronic constipation in children.
- The preparation offers rapid symptom relief and good tolerability in the pediatric population.
Abstract:
The aim of this study was to estimate the effectiveness of DUPHALAC preparation, produced by Solvay-Pharma, in treatment of functional chronic constipation. 112 children, aged 10 months-15.5 years were examined. DUPHALAC appeared to be very effective, were examined. Only two patients did not accept its taste. Rapidly (approximately after 2.5 weeks) improvement was achieved such as of restoration normal peristalsis and of previously disturbed defecation rhythm, softening of a stool, regression of pain and/or dyspeptic ailments, encopresis and improvement of appetite. In no case undesirable side effects were observed.