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Related Experiment Videos

Functional outcome in the elderly following lower extremity amputation

R G Frykberg1, S Arora, F B Pomposelli

  • 1Division of Podiatry, Beth Israel Deaconess Hospital, Harvard Medical School, Boston, MA, USA.

The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons
|June 25, 1998
PubMed
Summary

Major lower extremity amputation (LEA) in the very elderly significantly impacts survival and function. This study found high mortality and functional decline in patients aged 80+, regardless of diabetes status.

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Area of Science:

  • Geriatric Medicine
  • Vascular Surgery
  • Orthopedic Surgery

Background:

  • Functional outcomes and survival data for elderly patients undergoing major lower extremity amputation (LEA) are limited.
  • Diabetes mellitus is associated with significant mortality following LEA, with 5-year survival rates around 40% in the general diabetic population.
  • Understanding outcomes in the very elderly is crucial for limb salvage efforts and patient care.

Purpose of the Study:

  • To evaluate postoperative mortality and functional status in patients aged 80 years and above undergoing major LEA.
  • To compare outcomes between diabetic and non-diabetic patients in this elderly cohort.
  • To provide data clarifying the morbidity associated with LEA in the oldest populations.

Main Methods:

  • Retrospective review of 41 patients aged 80+ who underwent major LEA between 1990 and 1995.

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  • Analysis focused on postoperative mortality, functional status changes, and residential status.
  • Comparison of outcomes between patients with and without diabetes mellitus.
  • Main Results:

    • 55% of patients experienced worsened functional status post-operatively, and 32% had a decline in residential status.
    • Median survival was 19 months for diabetic patients and 49 months for non-diabetic patients.
    • Overall 5-year survival was 25%, with no statistically significant difference between diabetic and non-diabetic subgroups.

    Conclusions:

    • Major LEA in the very elderly population is associated with substantial mortality.
    • These procedures often lead to a deterioration in both functional and residential status.
    • The findings underscore the significant risks and poor prognosis following LEA in the oldest age groups.