Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Porcine major histocompatibility complex

M Vaiman1, P Chardon, M F Rothschild

  • 1Commissariat à l'énergie atomique/Institut national de la recherche agronomique, Département de radiobiologie et de radiopathologie, Jouy-en-Josas, France.

Revue Scientifique Et Technique (International Office of Epizootics)
|June 25, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A comparative whole genome sequencing analysis identified a candidate locus for lack of operculum in cultivated gilthead seabream (Sparus aurata).

Animal genetics·2021
Same author

An integrated approach combining soil profile, records and tree ring analysis to identify the origin of environmental contamination in a former uranium mine (Rophin, France).

The Science of the total environment·2020
Same author

Identification of a major locus determining a pigmentation defect in cultivated gilthead seabream (Sparus aurata).

Animal genetics·2020
Same author

Marker discovery and associations with β-carotene content in Indian dairy cattle and buffalo breeds.

Journal of dairy science·2019
Same author

Flow period influence on uranium and trace elements release in water from the waste rock pile of the former La Commanderie uranium mine (France).

Journal of environmental radioactivity·2019
Same author

Genome-wide scan reveals divergent selection among taurine and zebu cattle populations from different regions.

Animal genetics·2018
Same journal

Foreword - The World Organisation for Animal Health turns 100: reflections on the Organisation's role and evolution since 1924.

Revue scientifique et technique (International Office of Epizootics)·2024
Same journal

Preface - World Organisation for Animal Health: one hundred years at the service of animal health.

Revue scientifique et technique (International Office of Epizootics)·2024
Same journal

An appreciation of the seminal contributions of John Brooksby and Fred Brown on foot and mouth disease.

Revue scientifique et technique (International Office of Epizootics)·2024
Same journal

Are the knowledge, tools and resources to control foot and mouth disease available?

Revue scientifique et technique (International Office of Epizootics)·2024
Same journal

Rinderpest and peste des petits ruminants: a century of progress and the future.

Revue scientifique et technique (International Office of Epizootics)·2024
Same journal

Rinderpest and peste des petits ruminants: state of play in disease eradication efforts.

Revue scientifique et technique (International Office of Epizootics)·2024
See all related articles

The swine leukocyte antigen (SLA) complex on chromosome 7 influences pig immunity and reproduction. Selecting specific SLA haplotypes may enhance porcine production and disease resistance.

Area of Science:

  • Genetics
  • Immunology
  • Animal Science

Background:

  • The swine leukocyte antigen (SLA) complex, analogous to the human MHC, is crucial for immune function and disease resistance in pigs.
  • While the molecular organization of SLA class I and III regions is understood, the class II region requires further characterization.
  • Approximately sixty genes, including ten SLA class I sequences, have been identified, with functional polymorphic class I genes varying by haplotype.

Purpose of the Study:

  • To provide an overview of the swine leukocyte antigen (SLA) complex.
  • To highlight the genetic organization and known genes within the SLA complex.
  • To explore the associations between SLA haplotypes and important physiological traits in swine.

Main Methods:

  • Literature review and synthesis of existing research on the SLA complex.

Related Experiment Videos

  • Analysis of gene characterization and mapping data for SLA regions.
  • Examination of reported associations between SLA haplotypes and various physiological traits.

    • Main Results:

    • The SLA complex is located on chromosome 7, with distinct class I, II, and III regions.
    • Ten tightly packed SLA class I sequences are known, with 1-4 functional polymorphic genes per haplotype.
    • Significant associations exist between SLA haplotypes and immune response, as well as production and reproduction traits.

    Conclusions:

    • The SLA complex plays a significant role in swine physiology, particularly in immune response and reproductive performance.
    • Understanding SLA haplotype variations is key to comprehending these associations.
    • Selection for specific SLA haplotypes presents a potential strategy for improving porcine production and health outcomes.