Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Changes in core temperature and thermoeffector thresholds in exercise-trained rats

N Sugimoto1, O Shido, S Sakurada

  • 1Department of Physiology, School of Medicine, Kanazawa University, Kanazawa, 920-8640, Japan.

The Japanese Journal of Physiology
|June 25, 1998
PubMed
Summary

Exercise training in rats using running wheels increased resting and threshold core temperatures. This suggests exercise shifts thermoregulatory thresholds for heat loss and production to higher levels.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prognostic factors and treatment response in HER2-positive gastric cancer patients receiving trastuzumab deruxtecan: secondary analysis of the EN-DEAVOR study.

ESMO gastrointestinal oncology·2026
Same author

[Novel platelet pharming using human induced pluripotent stem cells].

Bulletin de l'Academie nationale de medecine·2020
Same author

Neutropenia and survival outcomes in metastatic colorectal cancer patients treated with trifluridine/tipiracil in the RECOURSE and J003 trials.

Annals of oncology : official journal of the European Society for Medical Oncology·2020
Same author

Rapid method for purification of Clostridium botulinuh type C neurotoxin by High Performance Liquid Chromatography (HPLC ).

European journal of epidemiology·2018
Same author

Platelet production from induced pluripotent stem cells.

Journal of thrombosis and haemostasis : JTH·2017
Same author

Principal component analysis uncovers cytomegalovirus-associated NK cell activation in Ph<sup>+</sup> leukemia patients treated with dasatinib.

Leukemia·2017

Area of Science:

  • Physiology
  • Exercise Science
  • Thermoregulation

Background:

  • Spontaneous running wheel activity is a common exercise model in small animal research.
  • Understanding exercise's impact on thermoregulation is crucial for animal physiology studies.

Purpose of the Study:

  • To investigate the effects of chronic running wheel exercise on core body temperature and thermoeffector thresholds in female rats.
  • To determine if exercise training alters the body's temperature regulation mechanisms.

Main Methods:

  • Female rats underwent 6 months of voluntary running wheel exercise.
  • Control rats remained sedentary.
  • Core and tail skin temperatures were monitored during controlled warming and cooling protocols to determine thermoeffector thresholds (vasodilation, thermogenesis).

Related Experiment Videos

Main Results:

  • Exercise-trained rats exhibited higher resting core temperatures compared to sedentary controls.
  • Threshold core temperatures for initiating tail skin vasodilation and cold-induced thermogenesis were elevated in the exercise-trained group.
  • These findings indicate a shift in thermoregulatory set points following exercise training.

Conclusions:

  • Chronic exercise training via running wheels elevates core body temperature in rats.
  • Exercise training shifts thermoeffector thresholds for heat loss and heat production to higher temperature levels.
  • This adaptation may contribute to a higher basal core temperature in exercise-trained animals.