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Chloroquine and cardiac arrhythmia: case report
R Siqueira-Batista1, A N Ramos Júnior, B S Pessanha
1Service Infectious Diseases, Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro, Brasil.
East African Medical Journal
|June 26, 1998
Summary
A sixty-two-year-old man experienced acute cardiac arrhythmia after treatment for Plasmodium vivax malaria with chloroquine. This case highlights a potential adverse drug reaction to a common malaria medication.
Area of Science:
- Cardiology
- Infectious Diseases
- Pharmacology
Background:
- Plasmodium vivax malaria is a significant global health concern.
- Chloroquine is a widely used antimalarial drug.
- Cardiac arrhythmias are serious potential side effects of medications.
Observation:
- A case report details a 62-year-old male patient diagnosed with Plasmodium vivax malaria.
- The patient developed acute cardiac arrhythmia during treatment.
- The arrhythmia was associated with the administration of chloroquine.
Findings:
- This case demonstrates a link between chloroquine use and the development of acute cardiac arrhythmia in a patient with Plasmodium vivax malaria.
- The specific type of arrhythmia and its severity are noted.
Implications:
- Clinicians should be vigilant for cardiac side effects when prescribing chloroquine for malaria.
- Further investigation into the mechanisms of chloroquine-induced cardiotoxicity may be warranted.
- This case underscores the importance of patient monitoring during antimalarial therapy.