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Percutaneous transmyocardial revascularization

C B Kim¹, S N Oesterle

¹Division of Cardiovascular Medicine, Stanford University School of Medicine, California 94305, USA.

Journal of Clinical Laser Medicine & Surgery

|June 26, 1998

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Transmyocardial revascularization (TMR) offers a new option for severe angina patients unsuitable for traditional treatments. This review focuses on developing a percutaneous transmyocardial revascularization (PMR) procedure, including animal studies and early human trials.

Area of Science:

Cardiovascular Surgery
Interventional Cardiology

Background:

Severe angina pectoris poses challenges for patients with complex coronary anatomy.
Traditional revascularization methods may not be suitable for all patients.

Purpose of the Study:

To review investigations of Transmyocardial revascularization (TMR).
To emphasize studies relevant to developing a percutaneous, catheter-based Transmyocardial revascularization (PMR) procedure.

Main Methods:

Review of existing TMR studies.
Analysis of preliminary animal studies on PMR.
Description of the PMR procedure.
Summary of the initiated human PMR protocol.

Main Results:

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Preliminary animal studies demonstrated the feasibility of PMR.

The human PMR protocol has been initiated, with early results to be determined.

Conclusions:

Percutaneous Transmyocardial Revascularization (PMR) is an evolving therapeutic option for refractory angina.
Further investigation is needed to establish the efficacy and safety of PMR.