Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Mediastinal fibrosis presenting as asthma

H Chantaphakul¹, M J Rock, D S Steiner

¹Department of Medicine, University of Wisconsin-Madison, USA.

Allergy and Asthma Proceedings

|June 27, 1998

Summary

Mediastinal fibrosis, a rare condition causing cardiopulmonary issues, can initially mimic common childhood asthma symptoms. Early diagnosis is crucial as it can be mistaken for other respiratory ailments.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

'When the dog bites': What can we learn about health geography from newspaper coverage in a 'model city' for dog-bite prevention?

Health & place·2019

Same author

Analytical and biological variation in repeated sweat chloride concentrations in clinical trials for CFTR modulator therapy.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2017

Same author

Endotypes of difficult-to-control asthma in inner-city African American children.

PloS one·2017

Same author

Association of ORMDL3 with rhinovirus-induced endoplasmic reticulum stress and type I Interferon responses in human leucocytes.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2017

Same author

Genetic associations with viral respiratory illnesses and asthma control in children.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2015

Same author

How rhinovirus infections cause exacerbations of asthma.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2014

Area of Science:

Pulmonology
Cardiology
Rare Diseases

Background:

Asthma is a common childhood respiratory condition.
Mediastinal fibrosis is a rare, incurable disease affecting the mediastinum.
Both conditions can present with similar respiratory symptoms.

Observation:

This report details two pediatric cases initially diagnosed with asthma.
These patients were later found to have mediastinal fibrosis.
Symptoms included wheezing, shortness of breath, and dyspnea on exertion.

Findings:

Mediastinal fibrosis can present variably, mimicking other respiratory diseases.
Early stages may be mistaken for asthma, chronic bronchitis, or superior vena cava syndrome.
The condition involves excessive fibrotic reaction leading to progressive cardiopulmonary compromise.

Implications:

Highlights the importance of considering rare diagnoses in pediatric respiratory cases.
Emphasizes the need for thorough differential diagnosis when asthma-like symptoms are present.
Suggests that early identification of mediastinal fibrosis is critical for patient management.

Related Experiment Videos