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Testicular histology in experimental uremic rats
Y Adachi1, I Sasagawa, T Tateno
1Department of Urology, Yamagata University School of Medicine, Japan.
Archives of Andrology
|June 27, 1998
Abstract:
Testicular histology in chronic renal failure was studied using stepwise-nephrectomized and adenine-treated rats. Serum levels of urea nitrogen and creatinine were significantly higher than those in sham-operated and control rats (P < .001). However, the mean tubular diameter was not different among the 4 groups. Numbers of A-spermatogonia, preleptotene and pachytene spermatocytes, and spermatids per 100 Sertoli cells were not different among the 4 groups. It would appear that testicular histology is not influenced by chronic renal failure in rats.