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Related Experiment Videos

Prospective, randomized trial comparing Micro Visc Plus and Healon GV in routine phacoemulsification

S A Arshinoff1, I Hofman

  • 1York Finch Eye Associates, Toronto, Ontario, Canada.

Journal of Cataract and Refractive Surgery
|June 27, 1998
PubMed
Summary

This study found that MicroVisc Plus and Healon GV sodium hyaluronate viscoelastics are safe and equally effective for phacoemulsification surgery. Higher viscosity agents may enhance surgical safety.

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Area of Science:

  • Ophthalmology
  • Surgical Innovation
  • Biomaterials Science

Background:

  • Sodium hyaluronate viscoelastics are crucial in ophthalmic surgery.
  • Evaluating novel, high-viscosity agents like MicroVisc Plus and Healon GV is important for improving surgical outcomes.

Purpose of the Study:

  • To compare the safety and efficacy of MicroVisc Plus and Healon GV in routine phacoemulsification.
  • To determine if high-viscosity, cohesive viscoelastics offer advantages over standard agents.

Main Methods:

  • A randomized, prospective clinical trial involving 100 eyes undergoing phacoemulsification.
  • Assessed safety and efficacy through visual acuity, corneal thickness, intraocular pressure, and surgeon feedback.
  • Compared results with a prior trial using standard viscosity viscoelastics (MicroVisc and Healon).

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Main Results:

  • No statistically significant differences in safety or efficacy were observed between MicroVisc Plus and Healon GV.
  • Surgeons found the two agents equivalent, though with slight differences in surgical facilitation.
  • The Healon GV/MicroVisc Plus group showed significantly less transient postoperative corneal thickening compared to the Healon/MicroVisc group.

Conclusions:

  • Healon GV and MicroVisc Plus are safe and yield comparable outcomes in phacoemulsification.
  • MicroVisc Plus's higher viscosity influenced its surgical handling compared to Healon GV.
  • Increased viscosity and cohesion in viscoelastic agents may enhance surgical safety.