Related Experiment Video
Updated: Aug 16, 2026

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
Published on: August 20, 2019
Taurodontism in children associated with trisomy 21 syndrome
1Ege University, Faculty of Dentistry, Department of Pedodontics, Bornova, Izmir, Turkey.
Abstract:
Taurodontism, the dental trait characterized by teeth with elongated pulp chambers and apical displacement of the bifurcation or trifurcation of roots, is reviewed in children with Trisomy 21 (Down) syndrome. Twenty-two patients were studied to determine the frequency of taurodontism. Eruption delay and congenitally lost teeth were also evaluated. While no taurodont teeth were found in control group in the same age group, the frequency percentage of taurodontism in our study was found as 66% (p < 0.01, Mann-Whitney test). Results indicate that taurodontism occurs with a greater than expected frequency in these patients. This increased frequency may be from a generalized amplified instability of development.
More Related Videos
09:39Generation of Induced Pluripotent Stem Cells from Turner Syndrome (45XO) Fetal Cells for Downstream Modelling of Neurological Deficits Associated with the Syndrome
Published on: December 4, 2021
10:23Three-Dimensional Cephalometric Landmark Annotation Demonstration on Human Cone Beam Computed Tomography Scans
Published on: September 8, 2023
Related Concept Videos
Meiosis I
Nondisjunction
Genomic Imprinting and Inheritance
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
Nondisjunction
Teratogenicity
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...