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Mineralisation density of human mandibular bone: quantitative backscattered electron image analysis
1Department of Anatomy and Developmental Biology, University College London, UK.
Journal of Anatomy
|June 27, 1998
Summary
Mandible bone mineral density increases with age, with higher density in older adults. Bone density varies by location, with lower density in areas of resorption and higher density in areas of functional strain.
Area of Science:
- Dental Anthropology
- Biomaterials Science
- Skeletal Biology
Background:
- Bone mineral density is a critical factor in mandibular biomechanics and remodeling.
- Understanding age-related changes and regional variations in mandibular mineralization is essential for dental and orthopedic applications.
Purpose of the Study:
- To investigate the distribution and age-related changes in mandibular bone mineral density.
- To correlate mineralization density with anatomical location and dental status.
Main Methods:
- Analysis of 88 adult human mandibles (age 19-96 years) using digital backscattered electron stereology.
- Sectioning of mandibles in midline, mental foramen, and third molar regions.
- Quantification of mineral density using a standardized grey level scale.
Main Results:
- Mineralization density significantly increased with age (r=0.70, P < 0.0001).
- Older individuals (>51 years) exhibited higher bone density than younger ones (16-50 years).
- Midline regions showed lower mineralization than mental foramen and third molar regions; alveolar bone was less dense than inferior cortex bone.
Conclusions:
- Mandibular bone mineralization density is strongly age-dependent.
- Regional variations in density correlate with functional strains and resorption sites.
- Local factors significantly influence the remodeling of the edentulous mandible.