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Reduction of intraocular pressure in a glaucoma patient undergoing hormone replacement therapy
M O Sator1, J Akramian, E A Joura
1Department of Obstetrics and Gynecology, General Hospital, University of Vienna, Austria. Michael.Sator@akh-wien.ac.at
Objectives:
To show the reducing effect of estrogens and progestins on the elevated intraocular pressure (IOP) in the case of a 56-year-old woman showing typical climacteric complaints, who was admitted to the menopause outpatient unit. She also suffered from a primary open-angle glaucoma treated with betaophtiole eye drops with intraocular pressures of 16-20 mmHg under this local therapy.
Methods:
IOP patterns were monitored by means of standardised daily pressure profiles four times a day before as well as 4 and 12 weeks after the beginning of hormone replacement therapy (HRT). The local glaucoma therapy remained unchanged.
Results:
During HRT, IOP levels were reduced from 16-20 mmHg before therapy to 12-15 mmHg at week 4 and to 13-15 mmHg at week 12 after the beginning of HRT.
Conclusion:
The finding of a close chronological relationship between the onset of menopause and the development of a glaucoma is a potentially new indication for HRT.