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New pyrrole alkaloids from Solanum sodomaeum
K A El Sayed1, M T Hamann, H A Abd El-Rahman
1The Department of Pharmacognosy and National Center for the Development of Natural Products and Research Institute of Pharmaceutical Sciences, University of Mississippi, University, Mississippi 38677, USA. elsayed@olemiss.edu
Journal of Natural Products
|June 27, 1998
Abstract:
Two new pyrrole alkaloids, solsodomine A and B, were isolated from the fresh berries of Solanum sodomaeum L., collected from the Libyan desert. The structures of these compounds were established by 2D-NMR, including 15N NMR spectroscopy and chemical degradation. Solsodomine A (1) shows activity against Mycobacterium intracellulare. This is the first report of pyrrole alkaloids from the genus Solanum.