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Dehydroradiosumin, a trypsin inhibitor from the cyanobacterium Anabaena cylindrica
S Kodani1, K Ishida, M Murakami
1Laboratory of Marine Biochemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113, Japan.
Journal of Natural Products
|June 27, 1998
Abstract:
Dehydroradiosumin, a novel potent trypsin inhibitory dipeptide, was isolated from the freshwater cyanobacterium Anabaena cylindrica (NIES-19). Its structure was elucidated as 1 on the basis of 2D NMR data and chemical degradation. The IC50 of 1 against trypsin was 0.1 microg/mL.