Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Effects of intake function shape on internal dose estimations

D Manuca1, K J Kearfott

  • 1Nuclear Engineering and Radiological Sciences, University of Michigan, Ann Arbor 48109-2104, USA.

Health Physics
|June 30, 1998
PubMed
Summary

Estimating internal radiation dose requires considering continuous intake, not just instantaneous intake, for accurate results. Continuous intake assumptions provide more precise dose evaluations, especially for longer integration times and specific radionuclides.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quantification of various factors influencing the precision of thermoluminescent detector calibrations for new and used chip sets.

Health physics·2011
Same author

Application of an equilibrium-based model for diffusion barrier charcoal canisters in a small volume non-steady state radon chamber.

Health physics·2011
Same author

Method of estimating lifetime cancer risk due to chronic radionuclide intake.

Health physics·2011
Same author

Simulation of a method for determining one-dimensional 137 Cs distribution using multiple gamma spectroscopic measurements with an adjustable cylindrical collimator and center shield.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2011
Same author

An equilibrium-based model for measuring environmental radon using charcoal canisters.

Health physics·2010
Same author

A numerical method for the calibration of in situ gamma ray spectroscopy systems.

Health physics·2010

Area of Science:

  • Radiological Sciences
  • Internal Dosimetry
  • Environmental Health Physics

Background:

  • Standardized computational procedures for internal dose estimation often assume instantaneous radionuclide intake.
  • This assumption can lead to inaccuracies, particularly for longer-term environmental exposures involving continuous intake.

Purpose of the Study:

  • To present solutions for kinetic equations modeling continuous activity intake in the respiratory system (RS) and gastrointestinal tract (GI).
  • To quantify the impact of continuous versus instantaneous intake assumptions on dose estimations.
  • To analyze the influence of radionuclide properties and integration times on dose calculation discrepancies.

Main Methods:

  • Solved first-order kinetic equations for ICRP 30 RS and GI models under continuous intake.

Related Experiment Videos

  • Computed cumulated disintegrations for various intake and integration times.
  • Compared dose estimations derived from continuous and instantaneous intake models for different radionuclide classes (D, W, Y).

    • Main Results:

    • For Class D compounds, dose estimations agreed within 10% for integration times >8 days.
    • For 141Ce (Class W), intake function affected dose by <10% for integration times >280 days, with GI being less sensitive than RS.
    • Dose for Class Y radionuclides (e.g., 89Sr, 90Sr) showed high sensitivity to intake assumptions and half-life, requiring long integration times (>650d for 89Sr, >18,000d for 90Sr) for 10% accuracy.
    • Instantaneous intake assumption consistently overestimates integrated dose for continuous intake.

    Conclusions:

    • Continuous intake modeling is crucial for accurate internal dose evaluation, especially for integration times <10 years.
    • The shape of the intake function significantly impacts dose calculations when non-instantaneous intakes are relevant.
    • Dose overestimation occurs when continuous intake is treated as instantaneous.