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Cutaneous angiosarcoma with eyelid involvement

K Gündüz1, J A Shields, C L Shields

  • 1Oncology Service, Wills Eye Hospital, Philadelphia, Pennsylvania 19107, USA.

American Journal of Ophthalmology
|June 30, 1998
PubMed
Summary
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Angiosarcoma is a rare and aggressive skin cancer affecting the eyelid, often presenting as bruise-like lesions. Despite radiotherapy, this angiosarcoma case showed poor prognosis with metastasis and eventual death.

Area of Science:

  • Dermatology
  • Oncology
  • Ophthalmology

Background:

  • Angiosarcoma is a rare malignant vascular tumor.
  • Eyelid skin angiosarcoma is exceptionally uncommon.
  • Early diagnosis is crucial for patient outcomes.

Observation:

  • An 82-year-old male presented with multiple maculopapular lesions, nodules, and edema on the face and eyelids.
  • Biopsy confirmed cutaneous angiosarcoma.
  • The tumor affected the central facial area, including the eyelids.

Findings:

  • The patient received radiotherapy (5,000 cGy) with partial tumor regression.
  • Post-treatment, extensive lymphedema developed.
  • Metastases to the parotid gland and bone were identified, leading to death within 3 months.

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Implications:

  • Cutaneous angiosarcoma has a poor prognosis, even with treatment.
  • It should be included in the differential diagnosis for eyelid tumors and edema.
  • Facial and eyelid presentations can be the primary manifestation of this aggressive cancer.