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Related Experiment Videos

Myelolipoma: CT and pathologic features

P J Kenney1, B J Wagner, P Rao

  • 1Department of Radiologic Pathology, Armed Forces Institute of Pathology, Washington, DC, USA.

Radiology
|July 1, 1998
PubMed
Summary
This summary is machine-generated.

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Myelolipomas are adrenal or extra-adrenal tumors. Larger lesions (>10 cm) are more prone to hemorrhage, and their CT appearance differs from isolated adrenal myelolipomas.

Area of Science:

  • Radiology
  • Pathology
  • Oncology

Background:

  • Myelolipomas are rare benign tumors composed of mature adipose tissue and hematopoietic elements.
  • They can occur in the adrenal glands or at extra-adrenal sites.

Purpose of the Study:

  • To correlate the clinical and pathological features of myelolipomas with their appearance on computed tomography (CT).

Main Methods:

  • A retrospective review of 86 myelolipomas in 74 patients from 1981-1997.
  • CT images were analyzed for location, size, calcification, hemorrhage, fat content, and pseudocapsule.
  • Pathologic findings were correlated with CT imaging characteristics.

Main Results:

  • 72 adrenal and 14 extra-adrenal myelolipomas were identified.

Related Experiment Videos

  • Four clinicopathologic patterns were observed: isolated adrenal, adrenal with hemorrhage, extra-adrenal, and myelolipomatous foci within other adrenal conditions.
  • Hemorrhage was more common in larger lesions (mean diameter 14.2 cm vs 9.9 cm).
  • Extra-adrenal myelolipomas were most often found in the retroperitoneum.
  • Myelolipomatous foci within other adrenal conditions were smaller, had lower fat content, and were more calcified.

    • Conclusions:

    • Myelolipomas can be adrenal or extra-adrenal masses.
    • Hemorrhage is a significant feature in larger myelolipomas (>10 cm).
    • CT imaging can differentiate isolated adrenal myelolipomas from myelolipomatous foci within other adrenal pathologies.