Medical management of ectopic pregnancy

In selected patients who are hemodynamically stable with an unruptured tubal pregnancy, systemic methotrexate has success rates comparable to laparoscopic salpingostomy. Larger randomized studies are necessary to adequately assess subsequent fertility. Local injection of methotrexate or other agents requires a sonographically visible ectopic as well as technical skills, and has less consistent success rates than that of systemic MTX therapy.