Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Symptomatic pituitary metastases

A Morita1, F B Meyer, E R Laws

  • 1Department of Neurological Surgery, George Washington University, Washington, DC, USA.

Journal of Neurosurgery
|July 1, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence and impact of solar lentigines: An international survey.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026
Same author

Patterns of regret for inadequate sun protection: A population-based study [HELIOS].

Journal of the European Academy of Dermatology and Venereology : JEADV·2026
Same author

Subcutaneous pedicle subunit flap for upper lip reconstruction.

JPRAS open·2025
Same author

Attitudes and behaviors regarding sun exposure in Japan compared to Europe and North America.

The Journal of dermatology·2024
Same author

Do regrets of parents about sun overexposure impact preventive measures applied on their children?

Journal of the European Academy of Dermatology and Venereology : JEADV·2023
Same author

Stimulating peristalsis improves esophagogastric junction observation during sedated esophagogastroduodenoscopy in children and adolescents.

Acta gastro-enterologica Belgica·2022
Same journal

Extent of resection as an independent predictor of survival for patients with glioblastoma as defined by the new WHO 2021 classification.

Journal of neurosurgery·2026
Same journal

Surgical treatment of schwannomas around the tarsal tunnel: a case series of 40 patients and systematic review of the literature.

Journal of neurosurgery·2026
Same journal

Direct targeting for focused ultrasound thalamotomy in the treatment of movement disorders.

Journal of neurosurgery·2026
Same journal

Development and internal validation of the Meningioma Functional Outcome Risk and Counseling Estimator 6 score, a point-based prognostic tool for predicting 6-week functional independence after intracranial meningioma resection.

Journal of neurosurgery·2026
Same journal

Connectional anatomy of the cerebellum: dentate nucleus and cerebellar peduncles from a surgical perspective.

Journal of neurosurgery·2026
Same journal

Press releases in neurosurgery: is scientific accuracy compromised in public reporting of neurosurgery research?

Journal of neurosurgery·2026
See all related articles

Symptomatic pituitary metastasis, often the first sign of breast or lung cancer, requires aggressive treatment. Surgical decompression and radiation therapy can improve survival and quality of life for these patients.

Area of Science:

  • Oncology
  • Endocrinology
  • Neurology

Background:

  • Pituitary gland metastasis presents diagnostic and therapeutic challenges.
  • Metastatic tumors to the pituitary are rare but can cause significant morbidity.

Purpose of the Study:

  • To analyze the clinical presentation, treatment strategies, and prognosis of patients with symptomatic pituitary metastasis.
  • To evaluate the impact of treatment on survival and quality of life.

Main Methods:

  • Retrospective review of 36 patients with symptomatic pituitary metastases.
  • Analysis of primary cancer types, presenting symptoms, and treatment outcomes.
  • Correlation of local tumor control with survival and symptom amelioration.

Main Results:

Related Experiment Videos

  • Breast and lung cancers were the most common primary sites (33% and 36%, respectively).
  • Common symptoms included diabetes insipidus, anterior pituitary insufficiency, and retroorbital pain.
  • Median survival was 180 days; 56% of patients presented with pituitary metastasis as the initial illness manifestation.
  • Local tumor control significantly improved survival (p < 0.05) and alleviated symptoms like painful ophthalmoplegia and visual field deficits.

Conclusions:

  • Aggressive treatment, including surgical decompression and radiation therapy, is recommended.
  • Multimodal therapy improves quality of life for patients with symptomatic pituitary metastasis.