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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
Chlorofluorocarbon-free inhalers: are we ready for the change?
M R Partridge1, A A Woodcock, A L Sheffer
1Chest Clinic, Whipps Cross Hospital, London, UK.
The European Respiratory Journal
|July 2, 1998
Summary
Chlorofluorocarbons (CFCs) are being phased out of inhalers due to ozone depletion. New, safe propellants are replacing CFCs in metered dose inhalers, ensuring continued treatment for respiratory conditions.
Area of Science:
- Environmental Science
- Pharmacology
- Public Health
Background:
- Chlorofluorocarbons (CFCs) deplete stratospheric ozone, increasing harmful UV-B radiation.
- The Montreal Protocol mandates a global ban on CFC production, with limited exceptions.
Purpose of the Study:
- To inform health professionals about the transition away from CFC-based metered dose inhalers.
- To ensure a seamless shift to new propellant inhalers for patients with airway disorders.
Main Methods:
- Identification and safety validation of new propellant alternatives.
- Reformulation of aerosolized medicines with new propellants.
- Clinical trials and market release of new inhaler products.
Main Results:
- New propellants have been identified and proven safe for use.
- First reformulated beta-agonist and corticosteroid inhalers are now available.
- Widespread product reformulation is anticipated within three years.
Conclusions:
- The transition to new inhaler propellants is a collaborative effort involving various stakeholders.
- Healthcare professionals must prepare for the widespread adoption of new inhaler technologies.
- Ensuring patient access to effective respiratory treatments during this transition is paramount.
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