Related Experiment Video
Updated: Oct 29, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
Pemphigus vulgaris on an old surgical scar: Koebner's phenomenon?
S Reichert-Penetrat1, A Barbaud, S Martin
1Service de Dermatologie, Hôpital Fournier, 36, quai de la Bataille, 54035 Nancy Cedex, France. s.reicher@chu-nancy.fr
Abstract:
Pemphigus is an autoimmune bullous skin disorder. Several cases have been reported to originate in traumatized areas or on a scar, suggesting Koebner's phenomenon. Pemphigus can either remain localized or subsequently extend. This paper reports on a 60-year-old man in whom pemphigus vulgaris began on a 40-year-old surgical scar. The pemphigus initially remained localized to the scar and subsequently extended after two months. The time to onset of this bullous disease on the scar was especially long, compared to that which has been previously reported in the literature. A few cases have been reported where pemphigus developed a few months to a few years after surgery. A time to onset exceeding 3 years is extremely rare.
Related Concept Videos
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Peptic Ulcer
Clinical Applications of Epidermal Stem Cells
Healing II: Complications
Endocarditis II: Clinical Features of Infective Endocarditis
Peptic Ulcer Disease III: Clinical Manifestations and Complications
