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Purpuric lichen nitidus

M Endo1, S Baba, H Suzuki

  • 1Department of Dermatology, Surugadai Nihon University Hospital, Surugadai Nihon University Hospital, 1-8-13, Kanda-Surugadai, Chiyodaku, Tokyo 101, Japan.

European Journal of Dermatology : EJD
|July 3, 1998
PubMed
Summary
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This study details a rare case of purpuric lichen nitidus, a skin condition presenting with hemorrhage on the palm and thigh. Microscopic analysis revealed vascular damage and unique deposits, explaining the bleeding in this purpuric variant.

Area of Science:

  • Dermatology
  • Pathology
  • Histopathology

Background:

  • Lichen nitidus is a rare inflammatory skin condition.
  • Hemorrhagic manifestations are uncommon in lichen nitidus.

Observation:

  • A patient presented with lichen nitidus lesions on the palm and thigh exhibiting hemorrhage.
  • Histopathological examination revealed significant changes in small vessels within the lesions.
  • Capillary walls showed degenerative changes and erythrocyte extravasation.

Findings:

  • Electron microscopy identified amorphous, electron-dense deposits external to endothelial cells.
  • These vascular and ultrastructural findings correlate with the observed hemorrhagic changes.
  • The case is characterized as purpuric lichen nitidus.

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Implications:

  • This case expands the clinical spectrum of lichen nitidus.
  • Understanding the vascular pathology may inform future diagnostic and therapeutic approaches.
  • Highlights the importance of detailed histopathological and ultrastructural analysis in rare dermatoses.