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ESD polymorphism in Norway

B Olaisen, P Teisberg, R Jonassen

    Human Genetics
    |September 10, 1976
    PubMed
    Summary
    This summary is machine-generated.

    This study analyzed esterase D (ESD) phenotype distribution and allele frequencies in Norwegian and Lapp populations. Results show good accordance with Hardy-Weinberg distribution, with similar ESD1 allele frequencies in both groups.

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    Area of Science:

    • Population genetics
    • Human genetics
    • Biochemical genetics

    Background:

    • Esterase D (ESD) is a enzyme encoded by the ESD gene.
    • Genetic variations in ESD can be population-specific.
    • Understanding ESD phenotype distribution is important for population genetics studies.

    Purpose of the Study:

    • To determine the phenotype distribution of Esterase D (ESD) in Norwegian and Norwegian Lapp populations.
    • To calculate the allele frequencies of ESD in these populations.
    • To assess the genetic variation within and between these groups.

    Main Methods:

    • Phenotyping for ESD was performed on samples from 217 Norwegians and 196 Norwegian Lapps.
    • Allele frequencies were calculated based on the observed phenotypes.

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  • Data was analyzed for accordance with Hardy-Weinberg equilibrium.

    • Main Results:

    • The study presents the ESD phenotype distribution for both Norwegian and Lapp populations.
    • ESD1 allele frequencies were found to be 0.887 in Norwegians and 0.872 in Lapps.
    • Observed genotype frequencies showed good accordance with Hardy-Weinberg distribution in both populations.

    Conclusions:

    • The genetic structure of Esterase D (ESD) in Norwegians and Norwegian Lapps is similar.
    • The populations adhere to Hardy-Weinberg equilibrium for ESD alleles.
    • These findings contribute to the understanding of genetic diversity in Scandinavian populations.