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[Trace elements in biological materials. Preanalysis safeguards]

V Senft1, J Racek, J Kohout

  • 1Ustav klinické biochemie a laboratorní diagnostiky LF UK a FN, Plzen.

Casopis Lekaru Ceskych
|July 3, 1998
PubMed
Summary
This summary is machine-generated.

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Accurate trace element analysis requires careful preanalytical safeguarding. Proper patient information, sample selection, and handling prevent result distortions from contamination.

Area of Science:

  • Clinical Chemistry
  • Analytical Chemistry
  • Environmental Health

Context:

  • Trace element analysis is crucial for diagnosing deficiencies or toxicities.
  • Preanalytical factors significantly influence the accuracy of trace element measurements.
  • Accurate quantification of elements like lead, mercury, and arsenic is vital for patient health.

Purpose:

  • To highlight the importance of preanalytical safeguarding in trace element analysis.
  • To outline essential steps for obtaining objective trace element data.
  • To prevent significant distortions in analytical results.

Summary:

  • Objective trace element analysis (Al, As, Cd, Cr, Co, Cu, Pb, Li, Mn, Hg, Ni, Se, Zn) necessitates strict preanalytical procedures.
  • Key steps include gathering patient data, selecting appropriate sample types and timing, and proper sample handling.

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  • Adherence to these principles minimizes contamination and ensures reliable results.

    • Impact:

    • Ensures the accuracy and reliability of trace element testing.
    • Prevents misdiagnosis related to trace element levels.
    • Improves patient outcomes by providing trustworthy diagnostic information.