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Related Experiment Videos

Eccentric roller type total artificial heart designed for implantation

M Sueshiro1, S Fukunaga, S Hirai

  • 1First Department of Surgery, Hiroshima University School of Medicine, Japan.

Artificial Organs
|July 3, 1998
PubMed
Summary
This summary is machine-generated.

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Researchers developed a novel, valveless total artificial heart using eccentric rollers. This implantable device successfully maintained circulation in an acute animal study, demonstrating its potential for cardiac replacement therapy.

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Devices
  • Implantable Systems

Background:

  • Development of implantable total artificial heart (TAH) systems is crucial for managing end-stage heart failure.
  • Existing TAH designs often face challenges with complexity, durability, and power consumption.

Purpose of the Study:

  • To develop and evaluate a novel eccentric roller type total artificial heart (TAH) for potential complete implantation.
  • To assess the performance of the valveless TAH using a mock circulatory system and acute animal experiments.

Main Methods:

  • An eccentric roller actuator with two torus-shaped silicone rubber blood chambers was designed and fabricated.
  • Performance was evaluated using a Donovan mock circulatory system, measuring flow rates and power consumption.

Related Experiment Videos

  • Ex vivo evaluation involved a 4-hour circulation test in an adult sheep.

    • Main Results:

    • The TAH operated effectively at roller speeds of 100-125 rpm, achieving flow rates of 2.5-3.0 L/min (right) and 3.2-3.8 L/min (left).
    • Electric power consumption ranged from 19.0-24.7 W.
    • The device demonstrated pulsatile ejection without motor reversal and sustained circulation in an adult sheep for 4 hours.

    Conclusions:

    • The developed valveless, eccentric roller TAH shows promising performance for pulsatile blood pumping.
    • This novel TAH design is a viable candidate for further development towards a completely implantable cardiac replacement system.