Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Implantable micropump system for augmented liver perfusion

O Marseille1, N Habib, H Reul

  • 1Helmholtz-Institute for Biomedical Engineering, Aachen, Germany.

Artificial Organs
|July 3, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Enormous Myoma Pedunculated Through the Cervix: A Surgical Challenge.

Case reports in obstetrics and gynecology·2025
Same author

Design and Evaluation of RNA Aptamer-Mediated Delivery of C/EBP<i>β</i> siRNA for Oncological Therapy.

Journal of nucleic acids·2025
Same author

Histological results of para-aortic lymph node dissection in patients with negative PET-CT for locally advanced cervical cancer in Reunion Island.

Journal of gynecology obstetrics and human reproduction·2025
Same author

Pudendal Neuralgia: Two case reports with laparoscopic nerve decompression.

Facts, views & vision in ObGyn·2023
Same author

A dusty veil shading Betelgeuse during its Great Dimming.

Nature·2021
Same author

Colorectal endometriosis: ample data without definitive recommendations.

Facts, views & vision in ObGyn·2021

A novel microaxial blood pump for the portal vein aims to improve liver function in cirrhosis patients. This implantable device enhances liver blood flow, reduces portal hypertension, and boosts metabolic activity.

Area of Science:

  • Biomedical Engineering
  • Hepatology
  • Medical Devices

Background:

  • Liver cirrhosis is a global health issue causing reduced liver blood flow, portal hypertension, and impaired metabolic function.
  • Current treatments for cirrhosis complications are limited in effectively restoring hepatic function and hemodynamics.

Purpose of the Study:

  • To propose and evaluate a novel microaxial blood pump for implantation in the portal vein.
  • To enhance hepatic blood flow and metabolic function in patients with liver cirrhosis.
  • To reduce elevated portal pressures to physiological levels.

Main Methods:

  • Development of a microaxial blood pump with a single-stage impeller powered by an integrated microelectric motor.
  • In vitro optimization of the pump design utilizing hydraulic performance and hemolysis testing.

Related Experiment Videos

  • The pump unit is designed for complete immersion within the blood vessel.

    • Main Results:

    • The microaxial pump design was optimized through in vitro hydraulic and hemolysis tests.
    • The device is intended to increase blood flow through the liver and enhance hepatic function.
    • The pump aims to reduce high pressures to physiological levels.

    Conclusions:

    • A microaxial blood pump offers a potential new therapeutic strategy for managing liver cirrhosis.
    • This technology could improve hemodynamics and metabolic function in the liver.
    • Further research and clinical trials are warranted to validate the efficacy and safety of this device.