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Structural divisions and functional fields in the human cerebral cortex

P E Roland1, K Zilles

  • 1Division of Human Brain Research, Department of Neuroscience, Doktorsringen 12, The Karolinska Institute, S-171 77 Stockholm, Sweden. Per.Roland@neuro.ki.se

Brain Research. Brain Research Reviews
|July 4, 1998
PubMed
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Defining cortical areas requires understanding both microstructural and functional borders. Research shows functional domains may not perfectly align with microstructural maps, impacting parallel processing in the brain.

Area of Science:

  • Neuroscience
  • Neuroanatomy
  • Cognitive Neuroscience

Background:

  • Defining cortical areas is complex, requiring integration of microstructural and functional data.
  • Existing methods for parcellation often focus on single criteria, neglecting the multi-faceted nature of cortical organization.

Purpose of the Study:

  • To thoroughly define cortical areas by examining borders in both microstructural and functional domains.
  • To investigate the relationship between microstructurally defined areas and functionally defined cortical fields.
  • To test the hypothesis that functional domains are equi-territorial to microstructurally defined meta-maps.

Main Methods:

  • Microstructural parcellation using quantitative measurements (neuron densities, receptor densities, enzyme densities).

Related Experiment Videos

  • Functional parcellation based on identifying cortical functional fields and population maps.
  • Intersection analysis to compare microstructural and functional domains.

    • Main Results:

    • Microstructurally defined areas appear as population maps due to inter-individual variations.
    • Cortical functional fields represent the largest functional entities, with the strong hypothesis suggesting cooperative computation within them.
    • Evidence of interference between tasks utilizing overlapping functional fields indicates limitations in parallel processing.

    Conclusions:

    • Functional domains are not necessarily equi-territorial to microstructurally defined areas.
    • Interference between tasks highlights restrictions in the human brain's parallel processing capabilities.
    • Separate functional streams for processing different types of information (e.g., visual, somatosensory) exist.