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Related Concept Videos

Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

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Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
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Heart Failure IV: Classification and Diagnostic Evaluation01:30

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Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
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Heart Failure VI: Adjunct Therapies01:22

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Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
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Cardiomyopathy II: Dilated Cardiomyopathy01:30

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Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
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Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

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Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
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Related Experiment Video

Updated: May 5, 2026

Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery
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Should we screen for asymptomatic left ventricular dysfunction to prevent heart failure?

J V McMurray1, T A McDonagh, A P Davie

  • 1MRC CRI in Heart Failure, University of Glasgow, U.K.

European Heart Journal
|July 4, 1998
PubMed
Summary

Screening for asymptomatic left ventricular dysfunction, a condition often preceding heart failure, is proposed. Early detection and treatment could be as effective as existing cancer screening programs.

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Area of Science:

  • Cardiology
  • Preventive Medicine
  • Medical Screening

Background:

  • Asymptomatic left ventricular dysfunction is a precursor to heart failure.
  • Existing screening programs for conditions like cancer are well-established.
  • The potential for early intervention in cardiovascular disease warrants investigation.

Purpose of the Study:

  • To evaluate the feasibility and principles of screening for asymptomatic left ventricular dysfunction.
  • To assess if such a program aligns with established screening criteria.
  • To determine if early detection and treatment can prevent heart failure development.

Main Methods:

  • The study proposes a screening program for asymptomatic left ventricular dysfunction.
  • It evaluates this program against the five established principles of screening.
  • Comparison is made with existing screening programs for cervical and breast cancer.

Main Results:

  • The proposed screening program appears to meet all five principles of screening.
  • The program's foundation is considered as robust as those for cervical and breast cancer screening.
  • Further evaluation is needed to confirm its efficacy.

Conclusions:

  • Screening for asymptomatic left ventricular dysfunction is a promising approach.
  • Such a program could be a valuable addition to preventive cardiovascular care.
  • More research is merited to validate this screening strategy.