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Effect of cataract on intraocular pressure
International Surgery
|August 1, 1976
Summary
Hypermature cataracts can cause increased intraocular pressure due to a phacolytic mechanism. This rise in eye pressure is linked to elevated protein levels and more macrophages in the aqueous humor.
Area of Science:
- Ophthalmology
- Cell Biology
Background:
- Cataract is a leading cause of vision impairment.
- Hypermature cataract presents unique clinical challenges.
Purpose of the Study:
- To investigate the relationship between cataract maturity and intraocular pressure.
- To elucidate the mechanism behind elevated intraocular pressure in hypermature cataracts.
Main Methods:
- Comparison of immature, mature, and hypermature cataract cases.
- Measurement of intraocular tension.
- Analysis of protein levels in aqueous humor.
- Quantification of macrophages in aqueous humor.
Main Results:
- Hypermature cataract cases exhibited significantly high intraocular tension.
- Elevated intraocular tension correlated with high protein levels in the aqueous.
- Increased macrophage counts were observed in the aqueous of hypermature cataract patients.
Conclusions:
- A phacolytic mechanism is implicated in the secondary increase of intraocular tension in hypermature cataracts.
- Protein leakage and inflammatory response contribute to elevated eye pressure.