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Updated: Aug 8, 2026

Probing the Structure and Dynamics of Interfacial Water with Scanning Tunneling Microscopy and Spectroscopy
Published on: May 27, 2018
Information from the water stripe in TOCSY experiments on systems with exchangeable protons
T T Nakashima1, R E McClung, G Kotovych
1Department of Chemistry, University of Alberta, Edmonton, Alberta, T6G 2G2, Canada.
Abstract:
The water "stripes" of the TOCSY maps of aqueous solutions of sucrose, of a 15-aminoacid peptide, and of several of the constituent aminoacids are shown to contain correlations at the resonance frequencies of protons which are scalar coupled to OH or NH protons which exchange with the solvent. Theoretical analysis of chemical exchange during the spin-lock period in TOCSY elucidates the origin of these correlations, and shows that their intensities vary with the duration of the spin-lock period and with the exchange rate.
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