[Coronary stent in acute myocardial infarction]
R Villavicencio Fernández1, A Marchena Noriega, G Eid Lidt
1Departamento de Hemodinámica, Instituto Nacional de Cardiología Ignacio Chávez INCICH, México, D.F.
Insights
Coronary stent implantation in acute myocardial infarction is a safe and feasible procedure. This study shows a low rate of recurrent ischemic events after stenting, improving patient outcomes.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Medicine
Background:
- Acute myocardial infarction (AMI) remains a leading cause of mortality worldwide.
- Timely reperfusion therapy is crucial for improving outcomes in AMI patients.
- Coronary artery stenting has emerged as a primary treatment modality for AMI.
Purpose of the Study:
- To evaluate the feasibility and safety of coronary stent implantation in patients with acute myocardial infarction.
- To assess the procedural success and clinical outcomes of stenting in AMI.
- To determine the rate of recurrent ischemic events following stent implantation for AMI.
Main Methods:
- A prospective study involving 50 patients with AMI who underwent 57 stent implantations between December 1995 and March 1997.
- Stents were implanted in various coronary arteries, including left anterior descending and right coronary arteries.
- Outcomes were assessed based on procedural success, TIMI flow, stenosis reduction, and clinical events at follow-up.
Main Results:
- Technical success rate was 100%, with clinical success in 96% of cases.
- Post-procedure TIMI 3 coronary flow was achieved in 92% of treated arteries.
- At a mean follow-up of 5.6 months, 73% of patients were in functional class I, with no recurrent ischemic events or deaths related to cardiac events.
Conclusions:
- Coronary stent implantation is a feasible and safe procedure for patients with acute myocardial infarction.
- The procedure demonstrates a low rate of recurrent ischemic events and favorable long-term clinical outcomes.
- Stenting effectively restores coronary blood flow and improves functional status in AMI patients.
Unlabelled:
From December 1995 to March 1997 fifty patients with acute myocardial infarction, had 57 stents implanted. Mean time since the beginning of symptoms to the procedure was 3.7 +/- 2.9 hours. Twenty-four stents were implanted "de novo", 17 for "sub-optimal" results, 5 for threatened closure and eleven for complex dissection. The arteries treated with stent were left anterior descending in 42%, right coronary in 42%, circumflex in 10%, vein grafts in 4%, intermedial branch in 1% and marginal obtuse branch in 1%. Stent used in most of the cases was AVE in 67% followed by Palmaz-Schatz, Wiktor, Crown, Gianturco-Roubin and Wallstent. Before procedure, coronary flow was TIMI 0 in 66% TIMI 1 in 10% and TIMI 2 in 24%. After procedure, TIMI 3 coronary flow was achieved in 92% of the arteries and other four had "no-reflow" phenomenon. Mean stenosis before procedure was 96% +/- 3.1 and after stenting was 1.76% +/- 2.6 with a stent/artery diameter rate of 1.01. Technical success was 100% and clinical success was achieved in 96% of the cases. Two cases were not successfully due to acute thrombotic closure in one patient and in another one because of cardiogenic shock after two days of a technical successful implantation of stent in LAD artery. There were not recurrent ischemic events (CABG, re-infarction or new coronary angioplasty procedure). Other two patients died for non-cardiac events (acute pancreatitis in one and by septic shock in other). At the time of discharge 96% of patients were treated with aspirin and ticlopidine. Major hematoma was evident in only one case. At a mean follow-up time of 5.6 months +/- 4.2 in 45 patients showed that 73% were in functional class I and none of them had re-infarction, death or needed a new revascularization.
Conclusion:
Stent implantation in acute myocardial infarction is feasible and safe procedure with a low rate of ischemic recurrent events.
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