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Assessment of memory in multiple sclerosis patients using the Memory Assessment Scale
Perceptual and Motor Skills
|July 10, 1998
Summary
Multiple sclerosis patients show significant verbal memory impairment. This study utilized a validated scale to confirm consistent deficits across different MS types, highlighting the need for reliable assessment tools.
Area of Science:
- Neuroscience
- Clinical Psychology
Background:
- Memory deficits in multiple sclerosis (MS) present inconsistently.
- Previous studies faced limitations including scale selection, psychometric properties, standardization, theoretical basis, and confounding variables.
Purpose of the Study:
- To assess verbal memory function in multiple sclerosis patients.
- To utilize the Memory Assessment Scale (MAS) to overcome limitations of prior memory assessments in MS.
Main Methods:
- Recruited 57 relapsing-remitting MS patients, 47 chronic progressive MS patients, and 132 controls.
- Administered verbal subtests of the Memory Assessment Scale.
- Conducted multivariate analysis controlling for age and verbal IQ.
Main Results:
- Both MS patient groups exhibited significantly diminished performance on most memory variables compared to controls.
- Verbal memory impairment was consistent across MS patient groups.
- List Clustering Acquisition was the exception, with MS patients performing similarly to controls.
Conclusions:
- The findings support significant and consistent verbal memory impairment in multiple sclerosis.
- The study underscores the importance of using psychometrically sound measures for memory assessment in MS populations.
