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Updated: Aug 11, 2026

Iris Fixation via External Pentagram Suturing
Published on: May 5, 2022
[Kinsbourne syndrome: review of our cases]
A C Rodríguez-Barrionuevo1, M A Caballero-Morales, M P Delgado-Marqués
1Sección de Neuropediatría, Hospital Materno-Infantil Carlos Haya, Málaga, España.
Introduction:
The childhood opsoclonus-myoclonus or Kinsbourne syndrome, is a uncommon process, of acute or subacute beginning, which affects infant and children. It's course is characterized by opsoclonus, polimyoclonias and cerebellar ataxia. The disease is frequently associated to neuroblastoma (46%).
Material And Methods:
We present a retrospective study on 9 patients, emphasizing the clinical presentation and the evolution aspects.
Results And Conclusions:
We found changes in the EEG in three cases. Most surprising is the scarce incidence of neuroblastoma, which has been found only in a one out of nine patients. We found three cases with relapse during the treatment or on withdrawal and one of them relapsed twice again. The evolution has been variable, since 5/9 patient have presented some type of mild or moderate neuro-psychological sequelae. Out of three patient with relapses, two presented permanent neurological sequelae. A patient which suffered three relapses, is also the one which presents more serious sequelae.
