Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prolactin, diuretics and urinary electrolytes in normal subjects

R Auty, R A Branch, E N Cole

    The Journal of Endocrinology
    |August 1, 1976
    PubMed
    Summary

    Plasma prolactin levels correlate with kidney electrolyte excretion in men. This study suggests an indirect relationship between prolactin and renal function, without evidence of negative feedback control.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    EELS: Autonomous snake-like robot with task and motion planning capabilities for ice world exploration.

    Science robotics·2024
    Same author

    Immune-mediated hematological disease in dogs is associated with alterations of the fecal microbiota: a pilot study.

    Animal microbiome·2023
    Same author

    Canadian Surgery Forum.

    Canadian journal of surgery. Journal canadien de chirurgie·2022
    Same author

    Vicsek model by time-interlaced compression: A dynamical computable information density.

    Physical review. E·2021
    Same author

    Predicting surgery waiting list volumes and health outcomes among people with an abdominal aortic aneurysm.

    The British journal of surgery·2021
    Same author

    Neuropathological and biochemical investigation of Hereditary Ferritinopathy cases with ferritin light chain mutation: Prominent protein aggregation in the absence of major mitochondrial or oxidative stress.

    Neuropathology and applied neurobiology·2020

    Area of Science:

    • Endocrinology
    • Nephrology
    • Human Physiology

    Background:

    • The interplay between endocrine hormones and renal function is complex.
    • Prolactin's role in electrolyte balance and its potential influence on kidney function require further elucidation.

    Purpose of the Study:

    • To investigate the relationship between plasma prolactin concentration and renal electrolyte excretion in healthy males.
    • To explore the impact of diuretics (frusemide) and aldosterone antagonists (spironolactone, prorenoate potassium) on this relationship.

    Main Methods:

    • Two studies involving six healthy male volunteers.
    • Administration of frusemide followed by dietary sodium restriction.
    • Comparison of spironolactone and prorenoate potassium effects against a placebo during sodium depletion.

    Related Experiment Videos

    Main Results:

    • Negative correlation between plasma prolactin and urinary sodium/potassium excretion after initial frusemide dose.
    • Positive correlation between plasma prolactin and urinary sodium excretion after prolonged sodium depletion and a second frusemide dose.
    • Altered correlations between plasma prolactin and urinary sodium/potassium ratio with spironolactone and prorenoate potassium administration.

    Conclusions:

    • Plasma prolactin concentration shows correlations with renal electrolyte excretion.
    • No evidence of a negative feedback control mechanism was observed.
    • The findings suggest an indirect relationship between prolactin and renal function.