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Mitomycin C-related hemolytic uremic syndrome in cancer patients
M E Schiebe1, W Hoffmann, C Belka
1Department of Radiotherapy, University of Tübingen, Germany.
Anti-Cancer Drugs
|July 11, 1998
Abstract:
In rare cases mitomycin C (MMC) may induce cancer-associated hemolytic uremic syndrome, which is characterized by hemolytic anemia, thrombocytopenia and progressive renal failure. Treatment possibilities of this multisystem disease up to now remain disappointing. We report a case of MMC-related hemolytic uremic syndrome, and discuss the etiologic parameters, clinical aspects, prognosis and treatment modalities of this severe syndrome.