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[Phase transition in the matrix as a regulator of enzymatic activity of proteinases]
1Department of Chemical Enzymology, Chemistry Faculty, Moscow State University, Russia.
Bioorganicheskaia Khimiia
|July 14, 1998
Abstract:
The kinetic behavior of proteolytic enzymes immobilized in thermosensitive hydrogels was studied at the phase transition (collapse) of the carriers. The dependence of the activity of immobilized enzymes on the state of the matrix allows the use of the hydrogel phase transition to regulate the activity of immobilized enzymes. Several cases of such regulation were demonstrated.