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Related Experiment Videos

Aging and primary central nervous system neoplasms

D T Blumenthal1, L M DeAngelis

  • 1Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

Neurologic Clinics
|July 17, 1998
PubMed
Summary
This summary is machine-generated.

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Primary brain tumors are increasing in older adults. While survival rates are stable for many, new treatments offer hope for specific tumor types, requiring personalized care considering health, tumor biology, and social factors.

Area of Science:

  • Neuro-oncology
  • Geriatric Medicine
  • Oncology

Background:

  • Increasing incidence of primary brain tumors in the aging population.
  • Overall survival rates for primary central nervous system neoplasms remain largely unchanged.
  • Emerging therapeutic advancements benefit select patient groups.

Purpose of the Study:

  • To review the challenges and considerations in managing primary brain tumors in elderly patients.
  • To highlight the impact of new treatments on specific brain tumor types in the geriatric population.
  • To emphasize a multidisciplinary approach to treatment planning.

Main Methods:

  • Literature review of recent studies on brain tumors in the elderly.
  • Analysis of treatment outcomes for various primary brain tumors.

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  • Discussion of factors influencing therapeutic decisions.

    • Main Results:

    • While overall survival has not dramatically improved, certain primary brain tumors show better outcomes with novel therapies.
    • Treatment decisions require careful evaluation of patient comorbidities and performance status.
    • Tumor biology and psychosocial aspects are critical for effective management.

    Conclusions:

    • Management of primary brain tumors in the elderly necessitates a comprehensive, individualized strategy.
    • Advances in neuro-oncology are improving outcomes for specific brain tumor subtypes in older adults.
    • Integrating medical, biological, and social factors is key to optimizing care for geriatric patients with brain tumors.