[Wiktor coronary stent for elective placement with an antiaggregation regimen. WINE study. WINE Group Study]

Area of Science:

• Cardiology
• Interventional Cardiology
• Vascular Medicine

Context:

• Coronary stent implantation presents risks like thrombosis and bleeding due to anticoagulation.
• The WINE study investigated an alternative antiplatelet-only regimen for Wiktor stent placement.

Purpose:

• To evaluate the safety and efficacy of aspirin and ticlopidine in patients undergoing elective Wiktor stent implantation.
• To assess complications and six-month restenosis rates with this antiplatelet-only strategy.

Summary:

• The WINE study included 368 patients, with 341 analyzed post-procedure.
• Subacute stent occlusion occurred in 0.6%, vascular complications in 2.1%, and no major bleeding events were reported.
• At six months, 19.8% of patients experienced angiographic restenosis.

Impact:

• This antiplatelet-only regimen demonstrates a very low rate of stent thrombosis and vascular complications.
• It offers a promising alternative to intensive anticoagulation, improving patient outcomes after Wiktor stent implantation.