Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

A system for inducing hyperthermia in sheep

G K Oakes, H Metz, R C Cefalo

Laboratory Animal Science

|August 1, 1976

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Mechanistic analysis of PLGA/HPMC-based in-situ forming implants for periodontitis treatment.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V·2015

Same author

In-vivo monitoring of acute DSS-Colitis using Colonoscopy, high resolution Ultrasound and bench-top Magnetic Resonance Imaging in Mice.

European radiology·2015

Same author

In-situ forming composite implants for periodontitis treatment: How the formulation determines system performance.

International journal of pharmaceutics·2015

Same author

A neonatal preventive intervention study: Issues of recruitment and retention.

The journal of primary prevention·2013

Same author

Sex and size in cosexual plants.

Trends in ecology & evolution·2011

Same author

Avoiding chaos.

Trends in ecology & evolution·2011

Same journal

Major histocompatibility haplotype does not impact the course of experimentally induced murine vaginal candidiasis.

Laboratory animal science·2000

Same journal

Pathologic changes associated with use of tribromoethanol (avertin) in the Sprague Dawley rat.

Laboratory animal science·2000

Same journal

Depressive effects of anesthesia or sedation on exocrine pancreatic function in pigs.

Laboratory animal science·2000

Same journal

Effects of histamine, carbachol, and methacholine on maximal expiratory lung mechanics in goats.

Laboratory animal science·2000

Same journal

Comparison of three treatments for control of ear mites in ferrets.

Laboratory animal science·2000

Same journal

Comparison of two systems for tibial external fixation in rabbits.

Laboratory animal science·2000

See all related articles

Researchers developed a novel system to induce controlled hyperthermia in pregnant sheep. This method reliably increased maternal core body temperature, offering a tool for studying heat stress effects during gestation.

Area of Science:

Veterinary Medicine
Physiology
Environmental Health

Background:

Hyperthermia during pregnancy poses risks to both mother and fetus.
Controlled experimental models are needed to study the physiological effects of heat stress in pregnant animals.

Purpose of the Study:

To design and validate a system for inducing consistent and reproducible hyperthermia in pregnant sheep.
To establish a reliable method for investigating the maternal physiological responses to elevated body temperatures.

Main Methods:

A closed environmental chamber was utilized to control ambient temperature and relative humidity.
Pregnant sheep were exposed to conditions (42°C, 75% RH) preventing metabolic heat dissipation.
Maternal core body temperature was monitored via the abdominal aorta.

Related Experiment Videos

Main Results:

The system successfully induced a steady and progressive increase in maternal core body temperature.
A mean temperature rise of 2.5°C in the maternal abdominal aorta was achieved.
The target temperature increase occurred within a consistent timeframe of 120 ± 17 minutes.

Conclusions:

The designed system provides a consistent and reproducible method for inducing hyperthermia in pregnant sheep.
This model is suitable for further research into the physiological impacts of heat stress on maternal and potentially fetal health.