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Updated: Aug 7, 2026

Temporal Quantification of MAPK Induced Expression in Single Yeast Cells
Published on: October 4, 2013
Metal-ion regulation of gene expression in yeast
D R Winge1, L T Jensen, C Srinivasan
1University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA. dennis.winge@hsc.utah.edu
Abstract:
Metal-responsive transcription factors exist in yeast to modulate expression of genes that encode proteins involved in cellular uptake of copper, iron and zinc ions. These signal transduction pathways function in the cellular regulation of the intracellular concentration of free metal ions. A second component of metal homeostasis is the regulation of metal-ion binding through protein-mediated metallation. Copper-specific chaperones exist in yeast that route copper ions to the site of biosynthesis of copper-metalloenzymes.
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