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Contact dermatitis with systemic symptoms from Agave americana
S Brenner1, M Landau, I Goldberg
1Department of Dermatology, Tel Aviv Sourasky Medical Center, Israel.
Dermatology (Basel, Switzerland)
|July 21, 1998
Summary
Agave americana exposure can cause significant contact dermatitis, including systemic effects. Dermatologists should consider self-inflicted plant exposure, especially with Agave americana, in patients presenting with these symptoms.
Area of Science:
- Dermatology
- Toxicology
- Plant-induced dermatitis
Background:
- Twelve cases of contact dermatitis caused by Agave americana exposure are detailed.
- A significant proportion of cases (10/12) presented with systemic signs and symptoms.
- Eight patients exhibited abnormal laboratory results.
Observation:
- Patient history indicated intentional exposure to Agave americana, often linked to soldiers seeking sick leave.
- Systemic symptoms and skin manifestations were observed following exposure.
Findings:
- Treatment with oral antihistamines and topical saline compresses led to rapid improvement.
- Systemic symptoms subsided within 24 hours of hospitalization.
- Cutaneous manifestations regressed within 7-10 days.
Implications:
- Dermatologists must be vigilant for self-inflicted contact dermatitis from plant exposure.
- Agave americana is a notable cause of plant-induced dermatitis with potential systemic involvement.
- Systemic signs associated with Agave americana exposure are not uncommon.