Infectious disease of the spine: outcome of rehabilitation

H L Yen1, K H Kong, W Chan

  • 1Department of Rehabilitation Medicine, Tan Tock Seng Hospital, Singapore.

Spinal Cord
|July 22, 1998
PubMed

Insights

Spinal infections, including pyogenic and tuberculous types, significantly improved functional outcomes and daily living activities following rehabilitation. Most patients achieved successful recovery and returned home.

Area of Science:

  • Rehabilitation Medicine
  • Infectious Diseases
  • Spinal Surgery

Background:

  • Spinal infections are uncommon in rehabilitation settings.
  • This study retrospectively analyzed patients with spinal infections undergoing rehabilitation.

Purpose of the Study:

  • To determine demographic characteristics, clinical features, and rehabilitation outcomes.
  • To compare outcomes between pyogenic and tuberculous spinal infections.

Main Methods:

  • Retrospective review of 26 patients with spinal infections over 6 years.
  • Analysis of demographic data, clinical presentation, treatment (surgery and antibiotics), and functional scores (motor, ADL, mobility).

Main Results:

  • Common pathogens included Staphylococcus aureus (pyogenic) and Mycobacterium tuberculosis.
  • Thoracic spine was the most frequent site; fever and neurological deficits were typical.
  • Significant improvements in motor scores, ADL, and mobility were observed for both infection types.
  • No significant difference in outcomes between pyogenic and tuberculous groups, except for ADL.

Conclusions:

  • Rehabilitation is effective for patients with spinal infections, leading to significant functional gains.
  • Demographics like age, gender, and diabetes did not significantly impact outcomes.
  • The majority of patients successfully completed rehabilitation and were discharged home.

Related Concept Videos

Secondary Spinal Cord Injury llI: Pathophysiology01:25

Secondary Spinal Cord Injury llI: Pathophysiology

Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...
Spinal Cord Injury ll: Pathophysiology01:14

Spinal Cord Injury ll: Pathophysiology

Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...
Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Degenerative Disc Disease ll: Pathophysiology01:23

Degenerative Disc Disease ll: Pathophysiology

The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...