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Updated: Oct 29, 2026

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations
Published on: January 10, 2015
[The coagulating and fibrinolytic activities of the blood in smokers]
Abstract:
A total of 110 essentially healthy male subjects 23 to 32 years old, with 80 of these smoking tobacco (cigarettes) were studied for the condition of coagulative and fibrinolytic activity with the aid of thromboelastograph and coagulograph. Measured in the venous blood plasma was concentration of fibrinogen. Also studied in the above male population were such parameters as completion of clot formation, time of reaction, time of coagulation, maximal elasticity of the clot, thromboelastographic index, maximum amplitude, and amplitude 10 minutes of the commencement of retraction and fibrinolysis, percentage of fibrinolysis. Smoking tobacco has been found out to make for enhancement of blood coagulative and fibrinolytic activities, particularly in persons with a more that 10-year history of smoking.
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