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The role of ifosfamide in paediatric cancer
1Department of Medical Oncology, Tata Memorial Hospital, Parel, Mumbai, India.
Australian and New Zealand Journal of Medicine
|July 23, 1998
Abstract:
Ifosfamide is an active drug in the therapy of paediatric tumours such as rhabdomyosarcoma, Ewings' sarcoma, Wilms' tumour, neuroblastoma, germ cell tumours and lymphomas. Myelosuppression is the major toxicity along with haemorrhagic cystitis. The latter is largely prevented by the use of concomitant mesna.